Mucoadhesive buccal drug delivery of drugs provides an attractive alternative to the oral route of drug administration, particularly in overcoming deficiencies associated with the latter mode of administration problems such as high first pass metabolism. Mucoadhesive buccal drug delivery systems offer many advantages over conventional systems such as ease of administration, rapid termination of therapy and administration to unconscious patients. Buccal mucosa makes a more appropriate choice of site if prolonged drug delivery is desired because buccal site is less permeable than the sublingual site.\r\nBuccal bioadhesive tablet formulations enable a delivery with a plasma drug level of the desired therapeutic response for a defined period of time, and also provides a means of confining the drug and penetration enhancer to a defined region of the mucosa.
Loading....